Classical drug discovery uses 2D cell culture coupled with animal testing for preclinical studies. Neither 2D cell culture nor animal testing truly recapitulate the in vivo microenvironments of cells in a human body. The paradigm shift is to use 3D cell culture in lab-on-a-chip devices that can faithfully mimic the in vivo conditions. With this modern drug discovery approach, costs can be reduced ten-fold, results can be achieved ten times faster, animal testing can be significantly reduced and personalized medicine can be realized. Therefore, Initio Biomedical, an Izmir Institute of Technology 's (IYTE) spinoff, is aimed to transform the pharmaceutical and medical industries today by developing lab-on-a-chip and organ-on-a-chip technologies.